In 1929, Charles L. Grigg of St Louis began selling a lemon-lime soft drink under the slogan “Takes the Ouch out of Grouch,” and it became a sensation.
One of the soft drink’s key ingredients was lithium, a powerful anti-depressant, which was removed in the 1940s.
The “7” in the name means seven ounces, while the “Up” is a reference to the carbonated bubbles rising to the surface.