King Tut and Cleopatra were related maybe in the sense that we’re all brothers and sisters and children of Mother Earth.
Apart from that, they were separated by 1,300 years and came from completely different bloodlines. Tutankhamen was a native Egyptian king.
Cleopatra was part of an interloper family that came from Greek Macedonia.
In fact, although she was the last of her line, she was the first of them to actually learn the language of the Egyptian people.